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KMID : 0357919810150040482
Korean Journal of Pathology
1981 Volume.15 No. 4 p.482 ~ p.488
Effects of Panax Ginseng Ethanol Extract on the Phagocytic Function of Reticuloendothelial System in Rats (Directed by Prof. Sang-Ho Kim)
À̵¿±Ù(×ÝÔÔÐÆ)/Dong-Geun Lee
Abstract
The present experiment was carried out to investigate the effects of Panax Ginseng
on the phagocytic function of reticuloendothelial system in rats. The phagocytic activity
was assessed by carbon clearance method after intraperitoneal administration of ginseng
extract with various dosage, namely 1, 5, 10, 20, 50mg per 100gm of body weight,
respectively.
The obtained results were followings :
1) In small dosage-treated group (1mg/100gm of B.W.), there were no significant
differences in phagocytic activity between treated and control group.
2) In large dosage-treated group(5, 10, 20 & 50mg/100gm of B.W.), the phagocytic
activity showed an increased level by time of twelve hours after injection except
temporary suppression on one hour after injection. Thereafter it returned gradually to
the normal level by the time of twenty-four hours.
From these results, it was concluded that the phagocytic function of reticuloendothelial
system was increased by the administration of appropriate dosage of ginseng extract.
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